THE UNIVERSITY OF QUEENSLAND

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Anaerobic short-chain gaseous alkane oxidation coupled to nitrate... Category: Humanities, Arts and Social Sciences (HASS) Research

ARC National Competitive Grants · FY 2025 · 2025-01

Scalable Bayesian inference for secure and reliable decision making. This project aims to develop the next generation of scalable Bayesian algorithms for fitting complex statistical models with big data. Existing scalable algorithms are either approximate or restricted to simple models with a small number of parameters. This can lead to unreliable data-informed decision making. Moreover, these methods are typically reliant on processing and storing big data at a central location which presents a higher risk to the privacy of the data. This project expects to significantly expand the set of problems where scalable Bayesian learning is practical and safe. This will lead to significant benefits for practitioners looking to make reliable decisions when working with big data. Field of research: 4905 - Statistics Comprehensive data-based insights are essential to decision making. They are needed for reliable decisions in industry and government, with an example being that the government uses data on transmission to decide on policy during pandemics. For these types of problems, it is necessary to have timely insights and to ensure the privacy of the often sensitive data. This project will develop new algorithms to enable these desires without relying on simplifying assumptions about the phenomenon of interest. The new methods will deliver timely insights to enable decision making under uncertainty, while preserving the privacy of the data being processed. This comes at a particularly relevant time as Australian companies are experiencing massive data breaches that have compromised the privacy of citizens and caused massive financial losses. The outputs of the research will be promoted through open access software, international talks, and podcasting to ensure outcomes of the research program are adopted and translated into real benefits for Australia.

ARC National Competitive Grants · FY 2025 · 2025-01

Harnessing the potential of natural peptides through chemical design. This project aims to re-engineer bioactive disulfide-rich peptides, such as those found in the venom of cone snails, to improve their therapeutic potential. These peptides are highly selective and potent towards a range of ion channels and receptors, but they suffer from rapid proteolytic degradation and poor permeability to cell membranes. This project focuses on developing strategies to improve their pharmaceutical properties to overcome obstacles in achieving oral bioavailability. Expected outcomes include new knowledge about structure-activity relationships, leading to a solid platform for the future development of peptide-based therapeutics, thereby resulting in considerable economic benefits. Field of research: 3404 - Medicinal and Biomolecular Chemistry Australian flora and fauna offer a wide range of bioactive peptides with potential applications in agriculture, biotechnology, and medicine. Nonetheless, these peptides are often unsuitable for direct use in their native forms due to their unfavourable pharmacokinetics. Thus, their intrinsic challenges must be solved to expand the utility of these natural peptides. This project will generate new knowledge and strategies to address the inherent drawbacks that will provide instrumental information for developing the next generation of peptide-based therapeutics. With approximately $70 billion global peptide therapeutics market, the project’s new IP will create significant commercial and economic benefits. The underpinning new and innovative approaches would have excellent prospects for industry investment, strengthening Australia’s global position as a leader in peptide therapeutics.

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Coral reef fish visual plasticity in the Anthropocene Category: Humanities, Arts and Social Sciences (HASS) Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

The brain-immune interface: implications for sleep and mood Category: Humanities, Arts and Social Sciences (HASS) Research

GrantConnect (Australian Government grants) · FY 2024 · 2024-12

Mobile DNA decides neuronal fate in the normal and degenerative human... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2024 · 2024-12

Complementary strategies to increase the utility of low-intensity... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2024 · 2024-12

Addressing Critical Knowledge Gaps to Improve Outcomes in Ovarian,... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2024 · 2024-12

Beyond the Cancer Care Divide: achieving First Nations health equity Category: Medical Research

GrantConnect (Australian Government grants) · FY 2024 · 2024-12

SPIDERMAP: Harnessing Spatial Epidemiology for Infectious Disease... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2024 · 2024-12

Venoms to drugs: translating venom peptides into human therapeutics Category: Medical Research

GrantConnect (Australian Government grants) · FY 2024 · 2024-12

Unlocking the Therapeutic Potential of Interleukin-22 Category: Medical Research

GrantConnect (Australian Government grants) · FY 2024 · 2024-12

Multidisciplinary initiatives to impact incidence and prevalence of STIs... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2024 · 2024-11

Terahertz Quantum Technology detecting the Invisible Melanom Category: Technology

GrantConnect (Australian Government grants) · FY 2024 · 2024-11

Development of an Advanced Flexible Chain-die Forming Process Category: Humanities, Arts and Social Sciences (HASS) Research

GrantConnect (Australian Government grants) · FY 2024 · 2024-11

Development of an Advanced Flexible Chain-die Forming Process Category: Humanities, Arts and Social Sciences (HASS) Research

GrantConnect (Australian Government grants) · FY 2024 · 2024-11

2024 Equipment Grants Category: Health and Medical Research

GrantConnect (Australian Government grants) · FY 2024 · 2024-11

Centre of Research Excellence in Mechanisms In NeuroDegeneration â€"... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2024 · 2024-11

Centre of Research Excellence in Mechanisms In NeuroDegeneration â€"... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2024 · 2024-10

Centre of Research Excellence in Mechanisms In NeuroDegeneration â€"... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2024 · 2024-10

Intergovernmental Panel on Climate Change Seventh Assessment Cycle... Category: Climate Change

GrantConnect (Australian Government grants) · FY 2024 · 2024-10

Aspiration and Respiratory Muscle Strength in Children Category: Medical Research

GrantConnect (Australian Government grants) · FY 2024 · 2024-10

Aspiration and Respiratory Muscle Strength in Children Category: Medical Research

GrantConnect (Australian Government grants) · FY 2024 · 2024-10

A co-designed framework to drive action to promote health and equity in... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2024 · 2024-09

The Early study: Evaluating the Specificity and feasibility of the EARLY... Category: Medical Research