MONASH UNIVERSITY

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Development and application of machine learning algorithms in... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Development of Innovative Small Molecules for Therapeutic Intervention... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Total recall: Exploiting human immune memory for smarter and safer Strep... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Exploring the proliferation potential of trabecular myocardium Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Dissecting the genetic diversity and therapeutic potential in targeting... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Novel liver-targeted therapy in liver cancer Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Targeting evolution to combat Helicobacter pylori antibiotic resistance Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Developing and Repurposing Therapies: Pioneering Interventional... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Advancing cluster randomised trials to the next generation: Development... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Novel approaches to enhance the quality of systematic reviews that... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Asian voyagers and First Nations people in Australia's Gulf of... Category: Humanities, Arts and Social Sciences (HASS) Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Improving the quality of survival after critical illness Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Rewiring the innate immune response to improve lung adenocarcinoma... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

G protein-coupled receptor Response Mechanisms to Environmental... Category: Humanities, Arts and Social Sciences (HASS) Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Leveraging electron microscopy to study receptor structure and function Category: Humanities, Arts and Social Sciences (HASS) Research

ARC National Competitive Grants · FY 2025 · 2025-01

Organosulfur surfactants as novel antioxidants. This projects aims to investigate new organosulfur-based surfactants for application in formulation science. The project expects to develop new surfactants and block copolymers that can attenuate oxidative stress, offsetting unwanted side effects or enhancing the function of pharmaceutical or agricultural formulations. Expected outcomes from the project include improved nanoparticle-based formulations incorporating the new organosulfur surfactants which are less harmful than previous formulations, and which can therefore be applied in diverse applications. This should provide significant benefits, such as agricultural formulations that improve crop yield or pharmaceutical and veterinary products that reduce side effects to the recipient. Field of research: 3406 - Physical Chemistry Liquid crystal nanoparticles are applicable to emerging applications in food science, agriculture and healthcare. As a result, the development of new surfactants and polymers that can be used to prepare such nanoparticles is a critically important endeavour, opening up new opportunities to develop new engineered materials with tuneable properties applicable in drug delivery, agricultural applications and veterinary medicine. The project has the potential to deliver economic and commercial benefits by providing opportunities for start-up companies, leading to employment and investment in Australian science and industry. Further, the new chemical entities synthesized will provide a robust intellectual property position for potential commercialisation, and the research team will work with industrial partners to develop these where appropriate. The project will provide additional national benefit by equipping PhD students and research fellows with strong cross-disciplinary skills that will be of benefit to industries recruiting graduates in science, technology and engineering. The project will enhance Australia's considerable international reputation as a leading country for colloid and interface science research.

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

How does RNA regulate gene repression? Category: Humanities, Arts and Social Sciences (HASS) Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Unravelling evolutionary effects of mitochondria on sperm and male... Category: Humanities, Arts and Social Sciences (HASS) Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Unravelling evolutionary effects of mitochondria on sperm and male... Category: Humanities, Arts and Social Sciences (HASS) Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Molecular Functions of Nicotinamide Adenine Dinucleotide Metabolites Category: Humanities, Arts and Social Sciences (HASS) Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Spatiotemporal control of microbial and biogeochemical activity in... Category: Humanities, Arts and Social Sciences (HASS) Research

ARC National Competitive Grants · FY 2025 · 2025-01

Uncovering heme regulation, handling & transport in mitochondria. Life is sustained through many important biochemical reactions that can extract energy and build new molecules for the cell to grow. Important to many of these reactions is a metal-containing molecule called heme. Heme is made in the mitochondria and it is still unclear what the consequences are when there is too much or too little of this molecule. Additionally, we do not know how heme gets out of mitochondria once made. This project addresses these two important questions using new and complementary approaches. Staff and students trained during this project will develop highly sought-after skills that will showcase Australian innovation and research capabilities and lead to new insights that will benefit agriculture and the life sciences. Field of research: 3101 - Biochemistry and Cell Biology This research project focuses on understanding the critical roles mitochondria play in animal cell function beyond their well-known role as the cell's powerhouse. Here, we will investigate how mitochondria produce, manage, and transport iron packaged into heme, which is essential for many proteins to function in cells. This study fills a significant research gap in Australia by exploring how mitochondria react to changes in heme levels and how heme travels from mitochondria to other cellular locations. Understanding heme regulation is crucial for farming and livestock, as excess heme causes mastitis in dairy cows, and environmental metal poisoning blocks heme synthesis leading to animal deaths, which is detrimental to Australia's $13 billion cattle industry. The processes discovered here may also benefit biotechnology by developing new heme-binding proteins that can improve human health or have industrial uses. To ensure our findings reach beyond academia, we will share discoveries through social media, highlight research in mainstream media, and engage with industry leaders who may benefit from this work. Additionally, this project will train the next generation of scientists, improve international collaborations by partnering with leading global research institutions, facilitating knowledge exchange and fostering future joint projects. These efforts aim to maximise the understanding, application and adoption of our research, ensuring it positively impacts Australian society

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Spatiotemporal control of microbial and biogeochemical activity in... Category: Humanities, Arts and Social Sciences (HASS) Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Protecting fertility, healthy pregnancy and long-term endocrine function... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

An Urgent Need for School Belonging: Meta-Analyses & Participatory... Category: Humanities, Arts and Social Sciences (HASS) Research