UNIVERSITY OF MELBOURNE

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Equitable reskilling for the future of work Category: Humanities, Arts and Social Sciences (HASS) Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Developing a laboratory-based model that mimics oral gonorrhoea... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Harnessing digital technologies to scale trauma-focussed mental... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Evidence based use of high-efficacy therapies in multiple sclerosis Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Metallic glass nanomaterials: New theory and syntheses Category: Humanities, Arts and Social Sciences (HASS) Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Variety is the spice of life: the mathematics of biological... Category: Humanities, Arts and Social Sciences (HASS) Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Do-It-Yourself Commemoration of the Dead Category: Humanities, Arts and Social Sciences (HASS) Research

ARC National Competitive Grants · FY 2025 · 2025-01

World-first pipeline for anti-blowfly drug discovery . Flystrike causes ~$320M in losses in Australian sheep production and threatens billions in international trade per year. New anti-blowfly drugs are urgently needed to combat wide-spread drug resistance and reduce surgical mulesing. This project aims to forge a world-first pipeline for anti-blowfly drugs using (1) genomics and genetic technologies to discover novel drug targets, (2) machine learning to prioritise targets and identify candidate drugs and (3) larval killing assays to validate these drugs for commercialisation. New drugs will improve flystrike management, animal welfare and production, and protect international trade markets, providing hundreds of millions of dollars in economic benefit to Australian sheep growers. Field of research: 3009 - Veterinary Sciences Blowfly strike costs the Australian sheep industry $320 million per annum and is primarily controlled through anti-blowfly drugs and management protocols (e.g., surgical mulesing). However, increasing drug resistance and rising pressure to cease mulesing due to animal welfare concerns requires new drugs. Our program addresses this critical research gap by leveraging world-class expertise to develop an integrated platform for blowfly drug development. This project will benefit Australians economically by ensuring the sustainability of the Australian sheep industry including $3.5 billion in domestic and $8.0 billion in global trade per annum. We need new drugs to counter widespread drug resistance, reduce the cost of blowfly strike on sheep and wool production, and reduce our reliance on mulesing, as a failure to do so risks Australian access to global trade markets. New drugs also have significant commercial value to the Australian sheep industry. To maximize understanding, translation and adoption of our research outcomes, we are actively engaging with our industry partner Australian Wool Innovation Limited (AWI) and will leverage their well-established network to communicate with sheep growers, including through AWI-led publications (Beyond the Bale), Blowfly Control Workshops (SimpliFly™), Websites (DemystiFly™), Webinars (It’s Fly Time!™) and AWI’s social media ensuring our findings are accessible, relevant, and directly inform policy and practical applications.

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Platform for Research and Interventions in youth Mental health and the... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Sexual violence against older women: Enhancing recognition and response Category: Humanities, Arts and Social Sciences (HASS) Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Unravelling Toxic Cyanobacterial Ecosystem Challenges in Wastewater... Category: Humanities, Arts and Social Sciences (HASS) Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Mooring offshore floating wind turbines onto Australian seabeds Category: Humanities, Arts and Social Sciences (HASS) Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Developing novel CAR T cells with enhanced metabolic performance for... Category: Medical Research

ARC National Competitive Grants · FY 2025 · 2025-01

Purpose beyond Profit: Modernising Corporations Law. In light of societal expectations that corporations take account of important social, environmental and cultural concerns, this project aims to make recommendations to enable corporations to pursue purposes beyond profit and to clarify the scope of directors’ duties in relation to these concerns. This will fill a significant gap in Australian legal scholarship. Key expected outcomes include empowering corporations to pursue public benefit purposes and reducing complexity and uncertainty for companies and directors. This is expected to provide significant benefits in enabling commercial activity that responds to societal expectations in relation to sustainability, climate change, biodiversity and human rights, as well as commercial benefits. Field of research: 4801 - Commercial Law Corporations exercise significant power and play a critical role in the economy. In the past the principal purpose of corporations was thought to be the pursuit of profit. However, society now expects corporations and their directors to consider important social, cultural and environmental concerns (such as sustainability, climate change, biodiversity and human rights) rather than focusing exclusively on the pursuit of profit. It is, however, difficult for Australian companies and their directors to do this because Australian corporate law is not fit-for-purpose. High profile international reports have suggested corporations be enabled to adopt formal purposes other than, or in addition to, profit as a solution. But there is no compelling way to do this in Australia due to unique features of our law. This project will make recommendations to modernise key aspects of corporate law to enable companies and their directors to pursue broader purposes. This will bring significant social, environmental and cultural benefits in enabling pursuit of public benefit purposes and encouraging commercial innovation and activity that achieves social, environmental and cultural purposes. It will also bring commercial and economic benefits in reducing complexity. Research outcomes will be broadly disseminated via networks of sector, industry and community bodies and committees, as well as by influential experts associated with the project.

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Preclinical development of a multidomain vaccine for... Category: Medical Research

ARC National Competitive Grants · FY 2025 · 2025-01

Bridging Worlds: Integrating Australian Indigenous Knowledges in Leadership. Current reconciliation processes and leadership models lack adequate integration of Indigenous Knowledges, hindering mutual understanding between Indigenous and non-Indigenous Australians. The project addresses this critical gap by co-creating leadership frameworks incorporating Australian Indigenous Knowledges into education, corporate and community leadership. Aligning with Reconciliation principles, the project promotes mutual understanding and shared decision-making. Outcomes include models for integrating Indigenous Knowledges, together with culturally sensitive guidelines. Benefits include fostering culturally responsive leadership, preserving Indigenous wisdom and enhancing Australia's capacity to address societal challenges. Field of research: 4501 - Aboriginal and Torres Strait Islander Culture, Language and History "Bridging Worlds: Integrating Indigenous Knowledges and Practices into Contemporary Leadership", addresses a critical gap in Australia's leadership landscape at a pivotal moment. As we face unprecedented global challenges, this innovative research has the potential to revolutionise our approach to leadership, positioning Australia as a world leader in inclusive and effective governance. By synergising Indigenous wisdom with contemporary practices, we aim to create transformative leadership models that could reshape our organisations, communities and national identity. This collaboration between universities, Indigenous-run organisations and industry partners promises to usher in a new era of uniquely Australian leadership. This research could benefit our nation by advancing reconciliation, enhancing our ability to address complex challenges, fostering innovation in organisational practices and contributing to Australia's reputation for inclusive and sustainable business practices. To ensure our findings reach beyond academia, we will create guides for businesses, host public workshops and an annual symposium, develop educational resources and engage with media and policymakers. We aim to advocate for including Indigenous leadership principles in national standards. By improving leadership with Indigenous insights, we strive to build a stronger, more inclusive Australia that is better equipped to face future challenges and lead on the global stage.

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Targeting JAG-1 for mucosecretory diseases Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Fungal Genomics and Antagonistic Community Interactions Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Chemokines as novel nucleic acid sensors: a new function in innate... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Enhancing mRNA vaccines by exploiting pathways of antigen presentation Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Defining neural regulation of the tumour immune ecosystem Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

A new way to see endometrial receptivity defects and implantation... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Host factors contributing to norovirus replication and transmission Category: Medical Research

ARC National Competitive Grants · FY 2025 · 2025-01

Metallic glass nanomaterials: New theory and syntheses. Our limited understanding of glassy (disordered) metallic nanoparticles is impeding the development of next-generation materials for biotechnology and clean energy. This project aims to use theory to guide fabrication of a new range of metal 'nanoglasses’. This is significant, because the properties of disordered materials can be vastly different from their crystalline counterparts, exhibiting enhanced plasticity, heat capacity, and chemical reactivity. Expected outcomes include a model for predicting the optical properties of nanoglasses and novel syntheses of gold-based nanoglasses, whose properties can be optimised at will. This should provide significant benefits, such as new options for cancer phototherapy and solar fuel synthesis. Field of research: 3407 - Theoretical and Computational Chemistry Metal nanoparticles have useful properties that have been harnessed to develop new biological sensors and new methods to generate clean fuels. This development was possible because the properties of crystalline materials are well understood. The properties of non-crystalline materials are not well understood. This project addresses this research gap, by studying a type of material called metallic nanoglasses. It is expected that the new nanoparticles developed in this project could more efficiently convert light energy into heat. This would make them ideal for new applications, such as in biotech, and lead to increased health benefits for Australians. This project will also seek to discover nanoglasses that can use energy from sunlight to speed up chemical reactions. Such particles could be used to permanently remove carbon dioxide from the atmosphere, creating an environmental benefit to Australians through its use in combating climate change. Taking the lead in developing and understanding these new materials will grow Australia’s standing as a world leader in nanomaterials research and allow us to train the next generation of innovators. We will seek local partnerships to commercialise applications of these new particles, which will benefit the Australian economy.

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Enhancing CD8+ T cell immunity using microbiota-derived short chain... Category: Medical Research