University of New South Wales

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Long-read sequencing methods and resources for genomic medicine Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Development of pre-clinical platforms for enhancing antibody quality in... Category: Medical Research

ARC National Competitive Grants · FY 2025 · 2025-01

Advanced Microcarriers for Cell-Based Manufacturing . This project aims to advance the manufacturing process of biologics, that require cells for the manufacturing process. Traditional methods like roller bottles or multilayer culture systems face challenges, including limited scalability and high costs. In collaboration with Sydney-based Smart MCs, we will develop and test innovative biomaterials to build next-generation xeno-free microcarriers for large-scale adherent cell culture, streamlining production, reducing costs, and enhancing quality. This initiative will strengthen Australia’s biotech industry, positioning the country as a leader in biopharmaceutical manufacturing and ensuring independence, especially during critical times like pandemics. Field of research: 4003 - Biomedical Engineering This project focuses on transforming the production of life-saving biologics by developing innovative, Australian-made technologies. Current manufacturing techniques face significant limitations in scalability, cost-effectiveness, and adaptability, hindering large-scale production. Our research will address these challenges by collaborating with a home-grown startup to create cutting-edge, materials known as microcarriers which allow cells to grow optimally. These advancements will streamline production, reduce costs, and improve the quality of biological therapies (biologics), positioning Australia at the forefront of biopharmaceutical manufacturing. This initiative aligns with Australian Government priorities, including the Advanced Manufacturing agenda and the National Reconstruction Fund, supporting the local biotechnology industry, creating high-skilled jobs, and reducing reliance on foreign supply chains. Ultimately, this project strengthens Australia’s leadership in biopharmaceutical manufacturing and ensures the country’s independence in producing critical medical supplies, contributing to national health security and resilience.

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

A cure for inflammatory bowel disease in mevalonate kinase deficiency Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Delving Deeper into the Matrix: Translating new stromal targets into... Category: Medical Research

ARC National Competitive Grants · FY 2025 · 2025-01

Understanding and overcoming cognitive inertia . This project aims to advance understanding of cognitive inertia, where decision-makers persist in choosing familiar but inferior decision options, and how to best respond to this problem. A new conceptual framework explaining how inertia develops will be tested through an integrated program of experimental research and computational modeling. The expected outcomes are advances in our understanding of the cognitive processes that drive inertia and how these may differ between individuals, and the development of more effective methods for preventing or reversing inertia. This will provide significant benefits by guiding better decision making in domains such as finance, environmental sustainability, and health. Field of research: 5204 - Cognitive and Computational Psychology Exploring one’s options is crucial to making decisions about complex issues relevant to everyday life (e.g., what sort of household energy plan should I purchase?). Problems in decision-making often arise through cognitive inertia - sticking with a familiar option when better alternatives are available (e.g., failing to consider a more sustainable energy plan that will be cheaper in the long run). However, the reasons why people often persist with choosing inferior options are not well understood. This project aims to evaluate a new model of cognitive inertia in order to improve decision quality. We will use the model to develop new ways of helping people to explore their options and hence make better decisions. Project results will be communicated to Australian government agencies and relevant industry stakeholders, and could lead to new ways of presenting information about decision options when communicating with the public. In turn, this will lead to communities that are better equipped to critically appraise the information they receive and subsequently make more informed decisions, including those guiding what we buy and how we live.

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Innovative strategies to reduce the global burden of stroke Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Innovative strategies to reduce the global burden of stroke Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Better use of established medicines Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Building the knowledge base for effective stigma reduction interventions... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Harnessing plasticity to prevent and treat metastatic and... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Using genomics to diagnose and manage patients with inherited cardiac... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Reducing the burden of infectious diseases using translational analytics Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Achieving HIV elimination and control of related conditions in gay and... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Optimising adult vaccination programs Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Reaching Global Targets for HPV Vaccination in Australia: Toward Equity... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Achieving HIV elimination and control of related conditions in gay and... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Gastrointestinal health and nutritional management of children with... Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Better use of established medicines Category: Medical Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Redefining the mechanosensory role of Transient Receptor Potential... Category: Humanities, Arts and Social Sciences (HASS) Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Visualising membrane pore assembly for cytosolic delivery of cargo... Category: Humanities, Arts and Social Sciences (HASS) Research

ARC National Competitive Grants · FY 2025 · 2025-01

Detecting A New Population of Circumbinary Planets via Apsidal Precession. This project aims to use a novel detection strategy to identify and characterise potentially 100 or more circumbinary planets, or planets which orbit two stars. The significance of this project is that it will enable us to understand the wide variety of environments in which small planets do or do not form, improving our understanding of the possible locations life may exist in the galaxy. Expected outcomes include a detailed understanding of how planets form in different environments. Benefits include a significant advance in the field of circumbinary planets under Australia's leadership, setting the stage for continued growth in this field with upcoming international facilities in which Australia is a partner. Field of research: 5101 - Astronomical Sciences This project aims to answer long-standing questions about how planets form around binary star systems, like the planet Tatooine in Star Wars. Different models of planet formation make different predictions about whether these types of planets form more or less easily when there are two stars in the system compared to when there is only one star. There are not enough detected planets orbiting binary stars to test these theories. We have developed a new method to identify these "circumbinary" planets, which we will be able to use to identify more than 100 planets. This effort will benefit Australia, building its research capacity in astronomy and placing it at the forefront of this burgeoning field. It will also enable future Australian leadership of the next generation of telescopes that will provide data to discover even more of these planets in the future. The team working on this project will work closely with international partners in North America and Europe, enabling the researchers funded through this project to highlight Australia's commitment to astrophysics and data-driven discovery on the world's stage. The technical data analysis and statistical methods developed in this work will be of broad interest and use to researchers in machine learning and related fields, strengthening links with industry partners across Australia.

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Two to Tango: The synergistic power of RNA-protein interactions in... Category: Humanities, Arts and Social Sciences (HASS) Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

A Probabilistic Approach to Big Data-Based Industrial Process Control Category: Humanities, Arts and Social Sciences (HASS) Research

GrantConnect (Australian Government grants) · FY 2025 · 2025-01

Delving Deeper into the Matrix: Translating new stromal targets into... Category: Medical Research